SCHEMBL14418686

SCHEMBL14418686

O=C1OCCC1OC(=O)C1C2CCC1C1C3CCC(C3)C21

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 4/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
POLB P06746 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 3/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9908431 0.85 TDP1 (0.41) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL14505692 0.83 ALDH1A1 (0.49) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL111761 0.74 ALDH1A1 (0.40) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL13633055 0.73 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL9908400 0.72 ALDH1A1 (0.43) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL2618680 0.72 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL13127570 0.72 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL14428683 0.71 KDM4E (0.45) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL14266976 0.71 KDM4E (0.43) KDM4EALDH1A1HPGDHSD17B10TDP1
SCHEMBL18641576 0.71 POLB (0.49) KDM4EALDH1A1HPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070212645-A1 Photo sensitive composition, pattern-forming method using the photosensitive composition and compound for use in the photosensitive composition FUJIFILM CORPORATION (JP) 2007-09-13 US disclosed
US-20070148595-A1 Resin having a monocyclic or polycyclic alicyclic hydrocarbon structure, of which solubility in an alkali developer increases under an action of an acid, a photoacid generator, methacrylic resins having hydrolysable ester groups and solvent; profiles; pattern collapse; immersion exposure; ARF lasers FUJIFILM CORPORATION (JP) 2007-06-28 US disclosed
US-20070141512-A1 Photosensitive composition, pattern-forming method using the photosensitve composition and compound in the photosensitive composition FUJIFILM CORPORATION (JP) 2007-06-21 US disclosed
US-20070134590-A1 Resin showing an increase in solubility in alkali developer by action of an acid, a compound being capable of generating an acid when irradiated with an actinic ray or radiation, an acrylic resin with silicon-containing units and being stable to acids but insoluble in alkali developer, solvent FUJIFILM CORPORATION. (JP) 2007-06-14 US disclosed
US-20070065752-A1 Positive resist composition and pattern forming method using the same FUJI PHOTO FILM CO., LTD. 2007-03-22 US disclosed