Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419424 | 0.89 | PTGDR2 (0.59) | PTGDR2TDP1TSHR | |
| SCHEMBL14419283 | 0.86 | PTGDR2 (0.61) | PTGDR2TDP1TSHR | |
| SCHEMBL14419286 | 0.86 | PTGDR2 (0.45) | PTGDR2TDP1MPOVNN1 | |
| SCHEMBL13715350 | 0.85 | PTGDR2 (0.55) | PTGDR2TDP1TSHRVNN1 | |
| SCHEMBL14419414 | 0.84 | PTGDR2 (0.50) | PTGDR2TDP1TSHR | |
| SCHEMBL14419280 | 0.84 | PTGDR2 (0.56) | PTGDR2TDP1TSHR | |
| SCHEMBL12955466 | 0.84 | PTGDR2 (0.54) | PTGDR2TDP1TSHR | |
| SCHEMBL8398940 | 0.84 | PTGDR2 (0.70) | PTGDR2TDP1TSHR | |
| SCHEMBL14419412 | 0.83 | PTGDR2 (0.51) | PTGDR2TDP1TSHR | |
| SCHEMBL14419284 | 0.83 | POLB (0.51) | MPOSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |