Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419283 | 0.90 | PTGDR2 (0.61) | PTGDR2TDP1TSHRMAPTTP53 | |
| SCHEMBL14419229 | 0.88 | PTGDR2 (0.57) | PTGDR2TDP1TSHRMAPTPKM | |
| SCHEMBL8398940 | 0.87 | PTGDR2 (0.70) | PTGDR2TDP1TSHRMAPTTP53 | |
| SCHEMBL14419297 | 0.86 | PTGDR2 (0.57) | PTGDR2TDP1TSHRMAPTTP53 | |
| SCHEMBL14419544 | 0.85 | PTGDR2 (0.68) | PTGDR2TDP1TSHRMAPTTP53 | |
| SCHEMBL14419292 | 0.85 | PTGDR2 (0.56) | PTGDR2TDP1TSHRMAPTTP53 | |
| SCHEMBL11541124 | 0.85 | CYP2C9 (0.56) | PTGDR2TDP1TSHRMAPTTP53 | |
| SCHEMBL14419279 | 0.85 | MAPT (0.47) | PTGDR2TDP1TSHRMAPTTP53 | |
| SCHEMBL14419301 | 0.85 | PTGDR2 (0.58) | PTGDR2TDP1TSHRMAPTFFAR1 | |
| SCHEMBL14419287 | 0.84 | PTGDR2 (0.60) | PTGDR2TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |