Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419478 | 0.89 | PTGDR2 (0.57) | POLBCYSLTR1PTGDR2MAPTPKM | |
| SCHEMBL11638829 | 0.84 | POLB (0.47) | POLBCYSLTR1PTGDR2MAPTMDM2 | |
| SCHEMBL14419477 | 0.84 | MAPT (0.50) | POLBCYSLTR1PTGDR2MAPTGAA | |
| SCHEMBL14419297 | 0.81 | PTGDR2 (0.57) | CYSLTR1PTGDR2MAPTGAASMN1; SMN2 | |
| SCHEMBL5627237 | 0.81 | PTGDR2 (0.57) | PTGDR2MAPTGAASMN1; SMN2LMNA | |
| SCHEMBL9209426 | 0.77 | TDP1 (0.62) | POLBPTGDR2MAPTTP53 | |
| SCHEMBL13715493 | 0.77 | PTGDR2 (0.44) | PTGDR2VNN1TP53 | |
| SCHEMBL9870159 | 0.76 | PTGDR2 (0.43) | POLBCYSLTR1PTGDR2MAPTSMN1; SMN2 | |
| SCHEMBL14419295 | 0.76 | MAPT (0.50) | POLBPTGDR2MAPTGAASMN1; SMN2 | |
| SCHEMBL14419484 | 0.76 | MAPT (0.63) | POLBMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |