Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5625621 | 0.86 | SMN1; SMN2 (0.56) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14419520 | 0.77 | MAPT (0.55) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5628999 | 0.76 | MAPT (0.57) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL27492213 | 0.76 | NPC1 (0.71) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14419478 | 0.76 | PTGDR2 (0.57) | MAPTPOLB | |
| SCHEMBL14419480 | 0.76 | POLB (0.47) | MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL5623365 | 0.75 | MAPT (0.56) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5625320 | 0.75 | TP53 (0.51) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL5623455 | 0.75 | TP53 (0.54) | MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14419384 | 0.74 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |