Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26239763 | 0.88 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL14420076 | 0.86 | ALDH1A1 (0.53) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL11476837 | 0.84 | PPARA (0.47) | CYP4F2CYP4A11ALDH1A1TLR7NPC1 | |
| SCHEMBL14420105 | 0.84 | CYP4F2 (0.46) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL26239742 | 0.82 | ALDH1A1 (0.53) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL26239722 | 0.82 | ALDH1A1 (0.53) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL14420065 | 0.82 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL27473665 | 0.79 | CYP4F2 (0.68) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL12062913 | 0.78 | ALDH1A1 (0.54) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL9000900 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | TLR7, CCR8, TLR8 | CYP4F2 1714/4885CYP4A11 457/4885ALDH1A1 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.