Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 4/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940586 | 0.94 | SLC22A12 (0.41) | SLC22A12PRMT5WDR77GPR119PIP4K2A | |
| SCHEMBL16492419 | 0.93 | EGFR (0.39) | SLC22A12EGFRPRMT5WDR77PIP4K2A | |
| SCHEMBL9950465 | 0.84 | SRC (0.54) | SRCEGFRGPR119 | |
| SCHEMBL515118 | 0.84 | SRC (0.54) | SRCEGFRGPR119 | |
| SCHEMBL16967987 | 0.79 | PIP4K2A (0.49) | SLC22A12SRCPRMT5WDR77PIP4K2A | |
| SCHEMBL514777 | 0.79 | GPR119 (0.43) | GPR119PIP4K2A | |
| SCHEMBL515111 | 0.79 | GPR119 (0.57) | SRCEGFRGPR119 | |
| SCHEMBL12649114 | 0.79 | PIP4K2A (0.42) | SLC22A12PRMT5WDR77GPR119PIP4K2A | |
| SCHEMBL26119378 | 0.79 | GPR119 (0.39) | SRCEGFRPRMT5WDR77GPR119 | |
| SCHEMBL13861581 | 0.78 | SRC (0.48) | SRCEGFRGPR119BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475668-A1 | ETHER DERIVATIVES OF BICYCLIC HETEROARYLS | Novartis AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029915-A1 | ETHER DERIVATIVES OF BICYCLIC HETEROARYLS | NOVARTIS AG (CH) | 2011-03-17 | — | — | WO | disclosed |