Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.78 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261614 | 1.00 | NR3C1 (0.78) | NR3C1PGRARTRPV1 | |
| SCHEMBL1261810 | 1.00 | NR3C1 (0.78) | NR3C1PGRARTRPV1 | |
| SCHEMBL1261615 | 1.00 | NR3C1 (0.78) | NR3C1PGRARTRPV1 | |
| SCHEMBL1261807 | 1.00 | NR3C1 (0.78) | NR3C1PGRARTRPV1 | |
| SCHEMBL1261962 | 1.00 | NR3C1 (0.78) | NR3C1PGRARTRPV1 | |
| SCHEMBL12893362 | 0.93 | NR3C1 (0.85) | NR3C1PGRARTRPV1 | |
| SCHEMBL1260274 | 0.93 | NR3C1 (0.85) | NR3C1PGRARTRPV1 | |
| SCHEMBL1260167 | 0.93 | NR3C1 (0.79) | NR3C1PGRARTRPV1 | |
| SCHEMBL1260208 | 0.93 | NR3C1 (0.79) | NR3C1PGRARTRPV1 | |
| SCHEMBL1260205 | 0.93 | NR3C1 (0.79) | NR3C1PGRARTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104582-A1 | TETRAHYDRONAPHTHALINE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-20 | — | — | WO | disclosed |