SCHEMBL14422008

SCHEMBL14422008

Cc1ncc2c(NC3c4ccc(F)c(O)c4[C@@H](C)C[C@]3(O)C(F)(F)F)cc(F)c(F)c2n1

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 7/20 0.61
PGR P06401 3/20 0.47
AR P10275 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1261624 1.00 NR3C1 (0.61) NR3C1PGRAR
SCHEMBL1261626 1.00 NR3C1 (0.61) NR3C1PGRAR
SCHEMBL3757443 1.00 NR3C1 (0.61) NR3C1PGRAR
SCHEMBL14421974 1.00 NR3C1 (0.61) NR3C1PGRAR
SCHEMBL12893349 0.93 NR3C1 (0.54) NR3C1PGRAR
SCHEMBL1260013 0.90 NR3C1 (0.65) NR3C1PGRAR
SCHEMBL1260012 0.90 NR3C1 (0.65) NR3C1PGRAR
SCHEMBL3748291 0.90 NR3C1 (0.65) NR3C1PGRAR
SCHEMBL1261341 0.89 NR3C1 (0.49) NR3C1PGRAR
SCHEMBL3748297 0.89 NR3C1 (0.77) NR3C1PGRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007104582-A1 TETRAHYDRONAPHTHALINE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2007-09-20 WO disclosed