Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213900 | 0.86 | KIT (0.54) | KITVCPC1RCBFBNPBWR1 | |
| SCHEMBL14422259 | 0.85 | MEN1 (0.50) | KITVCPCBFBNPBWR1MAPT | |
| SCHEMBL5214652 | 0.85 | KIT (0.52) | KITVCPCBFBNPBWR1CFTR | |
| SCHEMBL5219967 | 0.83 | KIT (0.47) | KITVCPALOX5CBFBMAPT | |
| SCHEMBL14422261 | 0.78 | PLAU (0.44) | KITALOX5PLAUMAPTMEN1 | |
| SCHEMBL5221543 | 0.78 | CBFB (0.41) | KITC1RCBFBNPBWR1 | |
| SCHEMBL5214660 | 0.77 | KIT (0.53) | KITCBFBNPBWR1 | |
| SCHEMBL5219975 | 0.76 | CBFB (0.54) | KITVCPCBFBNPBWR1NPY5R | |
| SCHEMBL6191101 | 0.74 | CBFB (0.47) | KITCBFBNPBWR1MAPTKDM4E | |
| SCHEMBL6176583 | 0.71 | CBFB (0.42) | KITCBFBNPBWR1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265138-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265138-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2007-09-04 | — | — | US | disclosed |