SCHEMBL14422342

SCHEMBL14422342

O=C1OC(c2ccccc2)=NC1=CS

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.63
NPC1 O15118 6/20 0.59
RAB9A P51151 6/20 0.59
DAPK3 O43293 1/20 0.55
F2 P00734 1/20 0.55
F10 P00742 1/20 0.55
PLG P00747 1/20 0.55
PLAU P00749 1/20 0.55
PLAT P00750 1/20 0.55
KLKB1 P03952 1/20 0.55
PLCG2 P16885 1/20 0.54
MAPT P10636 5/20 0.52
ALDH1A1 P00352 4/20 0.52
LMNA P02545 1/20 0.52
RECQL P46063 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CSNK2A2 P19784 1/20 0.52
CSNK2B P67870 1/20 0.52
CSNK2A1 P68400 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14000532 1.00 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL7298450 0.81 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL12914553 0.81 SMN1; SMN2 (0.68) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL7298453 0.81 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL4804024 0.81 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL24524106 0.81 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL4804018 0.81 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL12450700 0.81 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL21217197 0.81 SMN1; SMN2 (0.68) SMN1; SMN2NPC1RAB9ADAPK3F2
SCHEMBL2131623 0.80 DAPK3 (0.75) SMN1; SMN2NPC1RAB9ADAPK3F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7253826-B2 Thermal development apparatus FUJIFILM CORPORATION (JP) 2007-08-07 US disclosed
US-7253826-B2 Thermal development apparatus FUJIFILM CORPORATION (JP) 2007-08-07 US disclosed