Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456128 | 1.00 | APP (0.44) | APPNR4A2RXRARXRBCALM1 | |
| SCHEMBL14422350 | 0.95 | APP (0.47) | APPNR4A2RXRARXRBCALM1 | |
| SCHEMBL14461958 | 0.92 | APP (0.45) | APPNR4A2RXRARXRBCALM1 | |
| SCHEMBL14456177 | 0.90 | APP (0.44) | APPNR4A2RXRARXRBCALM1 | |
| SCHEMBL14456179 | 0.90 | APP (0.55) | APPNR4A2RXRARXRBMAOB | |
| SCHEMBL13592454 | 0.87 | GSTP1 (0.38) | APPNR4A2RXRARXRBCALM1 | |
| SCHEMBL14456122 | 0.84 | PARP10 (0.51) | APPNR4A2RXRARXRBMAOB | |
| SCHEMBL13609105 | 0.82 | MRGPRX4 (0.44) | APPPPARDPPARAPPARGESR1 | |
| SCHEMBL14456176 | 0.81 | MAOB (0.50) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL14456181 | 0.81 | MAOB (0.50) | MAOBLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259217-B2 | Controlled-architecture polymers and use thereof as separation media | SYMYX TECHNOLOGIES, INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-7259217-B2 | Controlled-architecture polymers and use thereof as separation media | SYMYX TECHNOLOGIES, INC. (US) | 2007-08-21 | — | — | US | disclosed |