SCHEMBL14422735

SCHEMBL14422735

C=C(C)C(=O)OCCOCCOC(=O)c1ccc2c(c1)n1n(-c3ccc(C(C)(C)C)cc3O)n21

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SERPINE1 P05121 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ POLB P06746 2/20 0.31
▸ APEX1 P27695 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ HTR7 P34969 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ HDAC6 Q9UBN7 1/20 0.30
▸ KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14422746 0.93 SERPINE1 (0.34) SERPINE1LMNATHRBPOLBAPEX1
SCHEMBL13159278 0.90 POLB (0.34) SERPINE1LMNAPOLBAPEX1HTT
SCHEMBL812950 0.90 POLB (0.34) SERPINE1LMNAPOLBAPEX1HTT
SCHEMBL14422745 0.86 ADRB2 (0.35) LMNA
SCHEMBL13300775 0.84 SERPINE1 (0.39) SERPINE1LMNAPOLBKDM4EHDAC6
SCHEMBL14422742 0.84 POLB (0.34) SERPINE1THRBPOLBAPEX1HTT
SCHEMBL813115 0.83 TDP1 (0.32) LMNAPOLBAPEX1HTTTDP1
SCHEMBL13159273 0.83 TDP1 (0.32) LMNAPOLBAPEX1HTTTDP1
SCHEMBL13159275 0.82 TYR (0.37) SERPINE1POLBAPEX1HTTTDP1
SCHEMBL812911 0.82 TYR (0.37) SERPINE1POLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070218218-A1 Cellulose acylate optical film, producing method thereof, polarizing plate and liquid crystal display using the same KONICA MINOLTA OPTO, INC. (JP) 2007-09-20 — — US disclosed
US-20070218218-A1 Cellulose acylate optical film, producing method thereof, polarizing plate and liquid crystal display using the same KONICA MINOLTA OPTO, INC. (JP) 2007-09-20 — — US disclosed
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