SCHEMBL14422758

SCHEMBL14422758

C=C(C)C(=O)OCCOc1ccc(NS(=O)(=O)c2ccc3c(c2)n2n(-c4cc(C(C)(C)C)ccc4O)n32)cc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.38
▸ PTPN5 P54829 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ MOGAT2 Q3SYC2 7/20 0.38
▸ POLB P06746 1/20 0.38
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ UQCRB P14927 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14422739 0.84 MAPT (0.38) LMNASMN1; SMN2POLBMAPTALDH1A1
SCHEMBL14422736 0.81 PTPN5 (0.34) PTPN5MEN1KMT2AMAPTALDH1A1
SCHEMBL14422757 0.80 ALDH1A1 (0.37) LMNAPTPN5SMN1; SMN2POLBMEN1
SCHEMBL812950 0.77 POLB (0.34) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL13159278 0.77 POLB (0.34) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL13300787 0.75 ALDH1A1 (0.43) LMNAPTPN5SMN1; SMN2POLBMEN1
SCHEMBL14422744 0.75 ESRRG (0.41) LMNASMN1; SMN2POLBMEN1KMT2A
SCHEMBL14422746 0.75 SERPINE1 (0.34) LMNAPOLBMEN1KMT2AKDM4E
SCHEMBL813160 0.74 KMT2A (0.35) SMN1; SMN2POLBMEN1KMT2AMAPT
SCHEMBL13159296 0.74 KMT2A (0.35) SMN1; SMN2POLBMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070218218-A1 Cellulose acylate optical film, producing method thereof, polarizing plate and liquid crystal display using the same KONICA MINOLTA OPTO, INC. (JP) 2007-09-20 — — US disclosed
Send feedback