SCHEMBL14422930

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14422922	0.92	RET (0.67)	RAF1KDRBRAFMAPK14RET
	SCHEMBL14422928	0.92	RAF1 (0.61)	RAF1KDRBRAFMAPK14RET
	SCHEMBL14422933	0.90	RAF1 (0.59)	RAF1KDRBRAFMAPK14RET
	SCHEMBL5635314	0.88	RAF1 (0.86)	RAF1KDRBRAFMAPK14RET
	SCHEMBL14422931	0.86	RAF1 (0.60)	RAF1KDRBRAFMAPK14RET
	SCHEMBL15574494	0.85	RAF1 (0.64)	RAF1KDRBRAFMAPK14RET
	SCHEMBL13004684	0.84	RAF1 (0.65)	RAF1KDRBRAFMAPK14RET
	SCHEMBL14422919	0.84	RET (0.62)	RAF1KDRBRAFMAPK14RET
	SCHEMBL13529089	0.83	RAF1 (0.72)	RAF1KDRBRAFMAPK14RET
	SCHEMBL22594900	0.83	RAF1 (0.75)	RAF1KDRBRAFMAPK14RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.