⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423313 | 0.82 | — | — | |
| SCHEMBL14423312 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL2800430 | 0.72 | KDM4E (0.30) | — | |
| SCHEMBL17986983 | 0.72 | — | — | |
| SCHEMBL14985651 | 0.72 | — | — | |
| SCHEMBL8916692 | 0.72 | — | — | |
| SCHEMBL3266137 | 0.72 | — | — | |
| SCHEMBL19233808 | 0.72 | — | — | |
| SCHEMBL14614515 | 0.72 | — | — | |
| SCHEMBL13431289 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | disclosed |
| US-7253169-B2 | Aza compounds, pharmaceutical compositions and methods of use | GLIAMED, INC. (US) | 2007-08-07 | — | — | US | disclosed |