Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082291 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL1368298 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL14824864 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL17252155 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL17616927 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL17252165 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL3842483 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL22627598 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL20613593 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA | |
| SCHEMBL301881 | 1.00 | ALDH1A1 (0.42) | ALDH1A1BCHEMAPTTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118571-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2019-06-20 | — | — | WO | disclosed |
| EP-2742083-B1 | POLYARYLENE ETHER KETONES | SOLVAY SPECIALTY POLYMERS USA (US) | 2018-04-25 | — | — | EP | disclosed |
| US-7252785-B2 | Composition of a radiation-absorbing tert-alkylphenoxy-substituted polycyclic ccmpound and a curable IR-reflecting component of achiral nematic polymerizable monomer, a chiral polymerizable monomer, a cholesteric polymerizable monomer, and a cholesteric polymer in a polymerizable diluent | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-07 | — | — | US | disclosed |