Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430141 | 0.91 | TRPA1 (0.74) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL14423747 | 0.85 | TRPV1 (0.73) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL14423752 | 0.85 | TRPA1 (0.70) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL13911578 | 0.85 | TRPV1 (0.56) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL14423772 | 0.84 | TRPV1 (0.72) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL15779635 | 0.84 | TRPV1 (0.78) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL14423746 | 0.84 | TRPV1 (0.78) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL13930770 | 0.83 | TRPV1 (0.70) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL13931352 | 0.82 | TRPV1 (0.76) | TRPA1KCNH2TRPM8TRPV1 | |
| SCHEMBL3710357 | 0.82 | TRPV1 (0.74) | TRPA1KCNH2TRPM8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256193-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2007-08-14 | — | — | US | disclosed |
| US-7256193-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2007-08-14 | — | — | US | disclosed |