Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL2511845 | 0.70 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| Propane SCHEMBL5726617 | 0.70 | MEN1 (0.61) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL12698795 | 0.69 | — | — | |
| SCHEMBL1104967 | 0.69 | TDP1 (0.52) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| Butane SCHEMBL10901332 | 0.67 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| Alcohol SCHEMBL10901320 | 0.67 | MEN1 (0.57) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL17612826 | 0.67 | MEN1 (0.57) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL27641853 | 0.67 | MEN1 (0.57) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| Bromide SCHEMBL11858025 | 0.65 | MEN1 (0.80) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| Benzidine SCHEMBL25422776 | 0.65 | TDP1 (0.73) | MAPTMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262318-B2 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER, INC. (US) | 2007-08-28 | — | — | US | disclosed |