Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL27933948 | 0.97 | MEN1 (0.53) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Benzidine SCHEMBL27812588 | 0.91 | CYP3A4 (0.65) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Alcohol SCHEMBL11649562 | 0.88 | MEN1 (0.44) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Alcohol SCHEMBL27513604 | 0.88 | MAOB (0.48) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| 4-Aminophenol SCHEMBL28648672 | 0.88 | ALDH1A1 (0.72) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Benzidine SCHEMBL28724221 | 0.88 | CYP3A4 (0.61) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Alcohol SCHEMBL3952222 | 0.88 | ACHE (0.72) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Sulfuric Acid SCHEMBL27914272 | 0.86 | TSHR (0.54) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Alcohol SCHEMBL27847089 | 0.86 | MEN1 (0.42) | MEN1MAPTKMT2AALDH1A1CYP3A4 | |
| Sulfurous Acid SCHEMBL9316262 | 0.86 | CYP3A4 (0.43) | MEN1MAPTKMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836430-A | Graphene-based composite heat conducting film and production process thereof | 安徽瑞鸿新材料科技有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-116425142-A | Schiff base-based metal nitrogen doped porous carbon material and preparation method and application thereof | 福州大学 | 2023-07-14 | — | — | CN | claimed |
| CN-116355547-A | Light-conversion solar cell packaging adhesive film and preparation method thereof | 宁波长阳科技股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| CN-111440077-B | Synthesis method of 2, 5-diaminophenylethanol sulfate and application thereof in antiallergic hair dye | 上海舒尔发化妆品科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-109369936-B | Preparation method of porous wave-absorbing film with block type Schiff base salt as main raw material | 河南工程学院 | 2021-06-08 | — | — | CN | claimed |
| CN-111205703-B | Crack visualized waterproof coating and preparation method thereof | 西南大学 | 2021-04-09 | — | — | CN | claimed |
| CN-111440077-A | Synthesis method of 2, 5-diaminophenylethanol sulfate and application thereof in anti-allergic hair dye | 上海舒尔发化妆品科技有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-111205703-A | Crack visualized waterproof coating and preparation method thereof | 西南大学 | 2020-05-29 | — | — | CN | claimed |
| CN-110183948-A | A kind of preparation method of alkylated polyphenyls amine/aqueous alkide resin composite anticorrosion coating | 陕西科技大学 | 2019-08-30 | — | — | CN | claimed |
| CN-109369936-A | A kind of preparation method of porous wave absorbing thin film that wanting raw material based on block type Schiff alkali salt | 河南工程学院 | 2019-02-22 | — | — | CN | claimed |
| CN-108424384-A | Ligand material and preparation method based on the double 8-hydroxyquinolines of p-phenylenediamine bridging | 广州工程技术职业学院 | 2018-08-21 | — | — | CN | claimed |
| CN-103524420-A | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | PROCTER & GAMBLE | 2014-01-22 | — | — | CN | claimed |
| CN-103242177-A | Preparation method of 2,5-diaminophenethyl alcohol sulfate | UNIV ZHEJIANG TECHNOLOGY | 2013-08-14 | — | — | CN | claimed |
| CN-101698647-B | Synthesis method of 2,5-diamino benzene ethanol | YIXING XINYU CHEMICAL CO LTD | 2012-10-03 | — | — | CN | claimed |
| CN-101698647-A | Synthesis method of 2,5-diamino benzene ethanol | YIXING XINYU CHEMICAL CO LTD | 2010-04-28 | — | — | CN | claimed |
| CN-117651546-A | Oxidation retardant composition | 莱雅公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117402271-B | Polyrotaxane covalent organic framework material with iodine adsorption function and preparation method and application thereof | 潍坊医学院 | 2024-02-23 | — | — | CN | disclosed |
| CN-1549700-A | Hair lightening colorants comprising direct dyes | P&G | 2004-11-24 | — | — | CN | disclosed |
| US-4588410-A | DEVELOPERS, COUPLERS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |
| US-4543425-A | 1,3-Diamino-4-(2',2',2',-trifluoroethoxy)-benzene, method of producing the same, and hair coloring composition containing the same | WELLA AG (DE) | 1985-09-24 | — | — | US | disclosed |