Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | CNR1 | P21554 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14424449 | 0.90 | HDAC1 (0.70) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL16363832 | 0.86 | NOX1 (0.63) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL29663991 | 0.82 | RAB9A (0.76) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10781905 | 0.81 | MAPT (0.67) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8803832 | 0.81 | KMT2A (0.66) | MAPTNPC1RAB9AGAAHDAC1 | |
| SCHEMBL14423994 | 0.81 | KMT2A (0.66) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10192175 | 0.81 | MEN1 (0.66) | MAPTNPC1RAB9ASMN1; SMN2CNR1 | |
| SCHEMBL14423986 | 0.81 | MAPT (0.76) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL28800706 | 0.80 | HDAC3 (0.57) | MAPTNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL23456385 | 0.79 | KMT2A (0.64) | MAPTNPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829876-A1 | NITROGENEOUS TRICYCLIC COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |