Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196033 | 0.99 | EPHX1 (1.00) | EPHX1ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL14424451 | 0.96 | EPHX1 (0.89) | EPHX1ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL14423982 | 0.90 | EPHX1 (0.79) | EPHX1ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL15975495 | 0.85 | EPHX1 (0.79) | EPHX1ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL12196199 | 0.83 | EPHX1 (1.00) | EPHX1ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL13480580 | 0.83 | EPHX1 (0.69) | EPHX1ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6438910 | 0.82 | EPHX1 (0.83) | EPHX1ALDH1A1HTTEPHX2MAPT | |
| SCHEMBL6270335 | 0.82 | EPHX1 (0.67) | EPHX1ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL7722626 | 0.82 | EPHX1 (0.97) | EPHX1ALDH1A1HTTLMNAEPHX2 | |
| SCHEMBL11034317 | 0.81 | EPHX1 (0.84) | EPHX1ALDH1A1HTTLMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829876-A1 | NITROGENEOUS TRICYCLIC COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |