Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 5/20 | 0.33 |
| ▸ | HK2 | P52789 | 5/20 | 0.33 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256228 | 0.83 | KDM4E (0.37) | KDM4ELMNACYP2D6CYP2C19HK1 | |
| SCHEMBL23705310 | 0.83 | KDM4E (0.37) | KDM4ELMNACYP2D6CYP2C19HK1 | |
| SCHEMBL23705263 | 0.83 | KDM4E (0.37) | KDM4ELMNACYP2D6CYP2C19HK1 | |
| SCHEMBL5680169 | 0.82 | CA12 (0.32) | — | |
| SCHEMBL3973511 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3675114 | 0.80 | PNP (0.30) | — | |
| SCHEMBL13880002 | 0.74 | — | — | |
| SCHEMBL20220892 | 0.74 | LMNA (0.38) | KDM4ELMNACYP2D6CYP2C19HK1 | |
| SCHEMBL7153776 | 0.70 | MAPK1 (0.47) | KDM4ELMNACYP2D6CYP2C19HK1 | |
| SCHEMBL7154585 | 0.70 | MAPK1 (0.47) | KDM4ELMNACYP2D6CYP2C19HK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071535-B2 | Guanidinium derivatives for improved cellular transport | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071535-B2 | Guanidinium derivatives for improved cellular transport | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-06 | — | — | US | disclosed |
| US-20070185040-A1 | Guanidinium derivatives for improved cellular transport | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185040-A1 | Guanidinium derivatives for improved cellular transport | SLC29A2, SLC29A1, SLC2A8 | KDM4E 3542/4885LMNA 1574/4885CYP2D6 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.