Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439551 | 0.85 | TERT (0.41) | TERTAPPMEN1KMT2AKCNH2 | |
| SCHEMBL21105269 | 0.84 | TRPV1 (0.38) | TERTAPPMEN1KMT2AKCNH2 | |
| SCHEMBL23118240 | 0.83 | SCN10A (0.47) | MEN1KMT2AKCNH2LMNAALDH1A1 | |
| SCHEMBL2707266 | 0.83 | SCN10A (0.47) | MEN1KMT2AKCNH2LMNAALDH1A1 | |
| SCHEMBL12025134 | 0.80 | CYP1A2 (0.57) | MEN1KMT2ALMNARAB9AKDM4E | |
| SCHEMBL2707037 | 0.80 | TSHR (0.39) | MEN1KMT2AKCNH2HRH3HTT | |
| SCHEMBL22521433 | 0.80 | KMT2A (0.39) | MEN1KMT2AKCNH2HRH3ALDH1A1 | |
| SCHEMBL22521368 | 0.79 | BACE1 (0.52) | MEN1KMT2AKCNH2HRH3ALDH1A1 | |
| SCHEMBL1695518 | 0.79 | TRPV1 (0.40) | MEN1KMT2AKCNH2HRH3ALDH1A1 | |
| SCHEMBL28334187 | 0.78 | PDE3B (0.40) | MEN1KMT2AKCNH2ACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197699-A1 | Novel substituted-polyaryl chromophoric compounds | TRANSPHOTONICS, LLC (US) | 2007-08-23 | — | — | US | disclosed |
| US-7205347-B2 | Substituted-polyaryl chromophoric compounds | TRANS PHOTONICS, LLC. (US) | 2007-04-17 | — | — | US | disclosed |