Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 12/20 | 0.81 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.81 |
| ▸ | TUBB | P07437 | 7/20 | 0.81 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.81 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.81 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.81 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.81 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.81 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.81 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.81 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.81 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.81 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.81 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.81 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129147 | 0.89 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6344292 | 0.85 | TUBB1 (0.70) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6776585 | 0.83 | TUBB1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6776580 | 0.83 | TUBB1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6129111 | 0.83 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6346609 | 0.83 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL6345988 | 0.82 | TUBB1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL6352937 | 0.82 | TUBB1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6355493 | 0.81 | TUBB1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27176082 | 0.81 | AKR1C2 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203224-A1 | SMALL-MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-08-30 | — | — | US | disclosed |
| US-20070203224-A1 | SMALL-MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-08-30 | — | — | US | disclosed |
| WO-2007081966-A2 | SMALL MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-07-19 | — | — | WO | disclosed |