Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 15/20 | 0.73 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.73 |
| ▸ | TUBB | P07437 | 9/20 | 0.73 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.73 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.73 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.73 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.73 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.73 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.73 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.73 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.73 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.73 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.73 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.73 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776580 | 1.00 | TUBB1 (0.73) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31032727 | 0.89 | TUBB1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5697760 | 0.86 | NQO2 (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5697759 | 0.86 | NQO2 (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7607439 | 0.85 | TUBB1 (0.67) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7607438 | 0.85 | TUBB1 (0.67) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6129147 | 0.83 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14427612 | 0.83 | TUBB1 (0.81) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15304532 | 0.83 | CES2 (0.62) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6346609 | 0.82 | TUBB1 (0.74) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677383-B1 | SUPRRESION OF TUMORS CONTAINING OXIDOREDUCTASE ENZYMES, BY CONTACTING THE CELLS WITH ANTITUMOR CHEMICAL INTERMEDIATES SUCH AS 3,4,5-TRIMETHOXY-4'-METHOXYSTILBENE | DE MONTFORT UNIVERSITY (GB) | 2004-01-13 | — | — | US | disclosed |
| EP-1051383-A1 | HYDROXYLATION ACTIVATED PRODRUGS | DE MONTFORT UNIVERSITY (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999040056-A1 | HYDROXYLATION ACTIVATED PRODRUGS | DE MONTFORT UNIVERSITY (GB) | 1999-08-12 | — | — | WO | disclosed |