Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22371802 | 0.86 | CA12 (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL22371820 | 0.86 | CA12 (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL22371805 | 0.82 | CA12 (0.44) | CA12CA1CA2CA9 | |
| SCHEMBL22189151 | 0.81 | CA12 (0.46) | CA12CA1CA2CA9 | |
| Diethylamine SCHEMBL6365058 | 0.81 | CA12 (0.52) | CA12CA1CA2CA9 | |
| SCHEMBL13084356 | 0.78 | CA12 (0.50) | CA12CA1CA2CA9 | |
| SCHEMBL5455649 | 0.78 | CA12 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL14428364 | 0.77 | BCHE (0.38) | — | |
| SCHEMBL6370201 | 0.77 | CA12 (0.56) | CA12CA1CA2CA9 | |
| SCHEMBL5461464 | 0.72 | MEN1 (0.46) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191372-A1 | Dna-targeted benzotriazine 1,4-dioxides and their use in cancer therapy | AUCKLAND UNISERVICES LIMITED (NZ) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191372-A1 | Dna-targeted benzotriazine 1,4-dioxides and their use in cancer therapy | HIF1AN, HIF1A, HYOU1 | CA12 1186/4885CA1 661/4885CA2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.