SCHEMBL14428633

SCHEMBL14428633

COC(=O)CCOC(=O)C1CC2CC1CC2C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
POLB P06746 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14487520 0.79 TSHR (0.34) TSHR
SCHEMBL14534915 0.78 EPHX2 (0.32) TSHRNPC1RAB9A
SCHEMBL13179065 0.77 CHRNB2 (0.39) TSHRMEN1KMT2A
SCHEMBL13893363 0.76 POLB (0.31) L3MBTL1POLB
SCHEMBL16021379 0.72 POLB (0.33) NPC1RAB9AL3MBTL1POLBMEN1
SCHEMBL16865161 0.67 POLB (0.42) NPC1RAB9AL3MBTL1POLBMEN1
SCHEMBL2979211 0.67 TSHR (0.57) TSHRRAB9AMEN1KMT2A
SCHEMBL14169407 0.67 MAPK1 (0.38)
SCHEMBL12429969 0.67 EPHX2 (0.31)
SCHEMBL22617434 0.67 CHRNB2 (0.46) TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7255971-B2 Positive resist composition FUJIFILM CORPORATION (JP) 2007-08-14 US disclosed
US-7235341-B2 Positive resist composition FUJIFILM CORPORATION (JP) 2007-06-26 US disclosed
US-20070141513-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-06-21 US disclosed
US-7214465-B2 Positive photosensitive composition FUJIFILM CORPORATION (JP) 2007-05-08 US disclosed