Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | AMD1 | P17707 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.46 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546911 | 0.87 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL21377709 | 0.87 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL25756742 | 0.87 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL2291014 | 0.87 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL25756772 | 0.87 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL24146635 | 0.87 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL14429049 | 0.86 | PI4KA (0.75) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL14429045 | 0.84 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL14208967 | 0.83 | POLB (0.61) | RXFP1ADORA1SMN1; SMN2P2RY1DNPH1 | |
| SCHEMBL24370870 | 0.83 | POLB (0.61) | RXFP1ADORA1SMN1; SMN2P2RY1DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | PI4KA 1438/4885PI4K2B 1989/4885PI4K2A 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.