Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.70 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.70 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.70 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.69 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.63 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.63 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.63 |
| ▸ | AMD1 | P17707 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377709 | 1.00 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL2291014 | 1.00 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL30546911 | 1.00 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL24146635 | 1.00 | PI4KA (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL13309395 | 0.90 | P2RX3 (0.64) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL1795275 | 0.89 | RXFP1 (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL1795964 | 0.89 | RXFP1 (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL1795283 | 0.89 | RXFP1 (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL1795966 | 0.89 | RXFP1 (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL14429043 | 0.87 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212213-A1 | A PLATFORM FOR SCREENING NAD+ BINDING PROTEINS IN A CELLULAR CONTEXT | UNIV OREGON HEALTH & SCIENCE (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212213-A1 | A PLATFORM FOR SCREENING NAD+ BINDING PROTEINS IN A CELLULAR CONTEXT | SARM1, PARP16, NAMPT | PI4KA 3648/4885PI4K2B 3024/4885PI4K2A 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.