Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429026 | 1.00 | PDE2A (0.48) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL1738386 | 0.96 | PDE2A (0.53) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL1738382 | 0.96 | PDE2A (0.53) | PDE2AADORA3ADORA2AADORA1ADRA1A | |
| SCHEMBL14440910 | 0.91 | LMNA (0.57) | ADORA3ADORA1LMNAMTORTHRB | |
| SCHEMBL1737852 | 0.90 | LMNA (0.58) | ADORA3ADORA1LMNAMTORTHRB | |
| SCHEMBL1737343 | 0.90 | LMNA (0.58) | ADORA3ADORA1LMNAMTORTHRB | |
| SCHEMBL6729928 | 0.90 | LMNA (0.58) | ADORA3ADORA1LMNAMTORTHRB | |
| SCHEMBL19843974 | 0.85 | LMNA (0.46) | ADORA3ADORA1LMNAMTORTHRB | |
| SCHEMBL14440250 | 0.83 | LMNA (0.45) | ADORA3ADORA1LMNAMTORTHRB | |
| SCHEMBL14429079 | 0.83 | SLC29A1 (0.54) | SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | PDE2A 3198/4885ADORA3 332/4885ADORA2A 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.