SCHEMBL1442973

SCHEMBL1442973

CCCOc1ccc(C(C)=O)cc1

nearest known ligand 0.78

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.78
GAA P10253 1/20 0.75
PLK1 P53350 1/20 0.66
MAPT P10636 3/20 0.64
ALDH1A1 P00352 1/20 0.64
LMNA P02545 2/20 0.59
POLB P06746 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HPGD P15428 1/20 0.57
RAB9A P51151 1/20 0.57
MAOB P27338 2/20 0.56
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.56
KDM4E B2RXH2 1/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PLA2G4B P0C869 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13139921 0.94 L3MBTL1 (0.70) L3MBTL1GAAPLK1MAPTALDH1A1
SCHEMBL5151604 0.94 L3MBTL1 (0.70) L3MBTL1GAAPLK1MAPTALDH1A1
SCHEMBL1092185 0.92 L3MBTL1 (0.85) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL18806580 0.90 L3MBTL1 (0.64) L3MBTL1GAAPLK1MAPTALDH1A1
SCHEMBL834525 0.90 L3MBTL1 (0.88) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL1470028 0.89 L3MBTL1 (0.85) L3MBTL1GAAMAPTALDH1A1TP53
SCHEMBL18868405 0.88 L3MBTL1 (1.00) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL4112694 0.87 MAPT (0.62) L3MBTL1GAAPLK1MAPTALDH1A1
SCHEMBL7733794 0.87 L3MBTL1 (0.60) L3MBTL1GAAPLK1MAPTALDH1A1
SCHEMBL7740048 0.87 L3MBTL1 (0.60) L3MBTL1GAAPLK1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP claimed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed
US-12155036-B2 Acid stratification mitigation, electrolytes, devices, and methods related thereto AMTEK RESEARCH INTERNATIONAL LLC (US) 2024-11-26 US disclosed
US-20240222702-A1 ACID STRATIFICATION MITIGATION, ELECTROLYTES, DEVICES, AND METHODS RELATED THERETO U.S. BANK NATIONAL ASSOCIATION 2024-07-04 US disclosed
US-11894517-B2 Acid stratification mitigation, electrolytes, devices, and methods related thereto AMTEK RESEARCH INTERNATIONAL LLC (US) 2024-02-06 US disclosed
EP-3130025-B1 COVALENTLY CROSS-LINKED GEL ELECTROLYTES AMTEK RES INTERNATIONAL LLC (US) 2021-07-07 EP disclosed
US-10199692-B2 Covalently cross-linked gel electrolytes AMTEK RESEARCH INTERNATIONAL LLC (US) 2019-02-05 US disclosed
US-10053526-B2 Catalyst for conjugated diene polymerization, conjugated diene polymer, modified conjugated diene polymer, polybutadiene, and compositions comprising foregoing UBE INDUSTRIES, LTD. (JP) 2018-08-21 US disclosed
US-20170158786-A1 CATALYST FOR CONJUGATED DIENE POLYMERIZATION, CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, POLYBUTADIENE, AND COMPOSITIONS COMPRISING FOREGOING UBE INDUSTRIES, LTD. (JP) 2017-06-08 US disclosed
US-9650362-B2 Inhibitors PROBIODRUG AG (DE) 2017-05-16 US disclosed
US-5015777-A Reaction of an acetophenone and an aliphatic ester or an ester of benzoic acid in the presence of sodium alkoxide condensation agent in an aromatic solvent WITCO CORPORATION (US) 1991-05-14 US disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed
US-4704396-A 5-HYDROXYTRYPTAMINE; HYPOTENSIVES ELI LILLY AND COMPANY (US) 1987-11-03 US disclosed
US-4536517-A ANTIDIABETIC, ANTILIPEMIC AGENTS AMERICAN CYANAMID COMPANY (US) 1985-08-20 US disclosed
US-4438277-A Hydronaphthalene derivatives SANKYO COMPANY, LIMITED (JP) 1984-03-20 US disclosed
US-4361515-A Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use SANKYO COMPANY, LIMITED (JP) 1982-11-30 US disclosed
US-4245093-A BY BROMINATION OF ALKANOYLOXYACETOPHENONES POST-TREATED WITH A TRIALKYL PHOSPHITE INHIBITS POLYBROMINATED BY-PRODUCTS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-01-13 US disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed