SCHEMBL14430301

SCHEMBL14430301

C=CC1=C(C(=O)OCS)N2C(=O)C(NC(=O)/C(=N\O)c3csc(N)n3)C2SC1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 8/20 0.78
▸ MAPT P10636 5/20 0.78
▸ ABCC4 O15439 2/20 0.78
▸ CNR1 P21554 1/20 0.78
▸ CTDSP1 Q9GZU7 1/20 0.78
▸ APEX1 P27695 3/20 0.68
▸ APAF1 O14727 2/20 0.68
▸ LMNA P02545 2/20 0.68
▸ L3MBTL1 Q9Y468 2/20 0.68
▸ TSHR P16473 1/20 0.68
▸ PLCG1 P19174 1/20 0.68
▸ ABCC2 Q92887 1/20 0.68
▸ SIRT5 Q9NXA8 1/20 0.68
▸ PSMD14 O00487 1/20 0.67
▸ MMP2 P08253 1/20 0.67
▸ PTGS1 P23219 2/20 0.56
▸ ALDH1A1 P00352 2/20 0.54
▸ HPGD P15428 2/20 0.54
▸ FAP Q12884 2/20 0.54
▸ USP2 O75604 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10529257 0.92 TDP1 (0.80) TDP1MAPTABCC4CNR1CTDSP1
SCHEMBL10529246 0.92 TDP1 (0.80) TDP1MAPTABCC4CNR1CTDSP1
SCHEMBL1745025 0.90 TDP1 (0.82) TDP1MAPTABCC4CNR1CTDSP1
SCHEMBL14441325 0.90 TDP1 (0.82) TDP1MAPTABCC4CNR1CTDSP1
SCHEMBL10526980 0.89 TDP1 (0.73) TDP1MAPTABCC4CNR1CTDSP1
SCHEMBL10526986 0.89 TDP1 (0.73) TDP1MAPTABCC4CNR1CTDSP1
Cefdinir SCHEMBL36995 0.88 TDP1 (1.00) TDP1MAPTABCC4CNR1CTDSP1
Cefdinir SCHEMBL3297328 0.88 TDP1 (1.00) TDP1MAPTABCC4CNR1CTDSP1
Cefdinir SCHEMBL4114437 0.88 TDP1 (1.00) TDP1MAPTABCC4CNR1CTDSP1
Cefdinir SCHEMBL2221924 0.88 TDP1 (1.00) TDP1MAPTABCC4CNR1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070191602-A1 Crystalline form of cefdinir cesium salt TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2007-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070191602-A1 Crystalline form of cefdinir cesium salt RCSD1, CHLSN, CES1 TDP1 4681/4885MAPT 1335/4885ABCC4 1263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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