Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643117 | 0.90 | GCK (1.00) | GCKKDM4ESMN1; SMN2NPC1MITF | |
| SCHEMBL2643373 | 0.88 | GCK (0.64) | GCKKDM4ENPC1RAB9ALMNA | |
| SCHEMBL2643455 | 0.87 | GCK (0.82) | GCKKDM4ESMN1; SMN2NPC1MITF | |
| SCHEMBL2643904 | 0.85 | GCK (0.83) | GCKKDM4ESMN1; SMN2NPC1MITF | |
| SCHEMBL2643522 | 0.84 | GCK (0.84) | GCK | |
| SCHEMBL2643912 | 0.82 | GCK (0.84) | GCK | |
| SCHEMBL2642949 | 0.82 | GCK (0.81) | GCKKDM4ENPC1RAB9A | |
| SCHEMBL2643973 | 0.81 | GCK (0.80) | GCKKDM4ENPC1RAB9A | |
| SCHEMBL2642904 | 0.81 | GCK (0.80) | GCKKDM4ENPC1RAB9A | |
| SCHEMBL2642942 | 0.81 | GCK (0.82) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |