SCHEMBL2643912

SCHEMBL2643912

Cc1csc(NC(=O)c2cc(Oc3ccc(F)cc3F)ccc2N)n1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GCK P35557 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2643455 0.90 GCK (0.82) GCK
SCHEMBL2643497 0.89 GCK (1.00) GCK
SCHEMBL2643609 0.89 GCK (0.74) GCK
SCHEMBL2643122 0.88 GCK (0.82) GCK
SCHEMBL2644042 0.87 GCK (0.72) GCK
SCHEMBL2642949 0.84 GCK (0.81) GCK
SCHEMBL2643117 0.84 GCK (1.00) GCK
SCHEMBL2642904 0.83 GCK (0.80) GCK
SCHEMBL2643973 0.83 GCK (0.80) GCK
SCHEMBL14430962 0.82 GCK (0.82) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1496052-B1 NOVEL AMINOBENZAMIDE DERIVATIVE BANYU PHARMA CO LTD (JP) 2009-08-05 — — EP disclosed
US-7253188-B2 Aminobenzamide derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-07 — — US disclosed
US-7253188-B2 Aminobenzamide derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-07 — — US disclosed
US-7253188-B2 Aminobenzamide derivative BANYU PHARMACEUTICAL CO., LTD. (JP) 2007-08-07 — — US disclosed
EP-1496052-A1 NOVEL AMINOBENZAMIDE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-01-12 — — EP disclosed
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