Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430975 | 0.87 | GCK (0.61) | GCKLMNA | |
| SCHEMBL14430951 | 0.80 | GCK (0.65) | GCK | |
| SCHEMBL2643624 | 0.80 | GCK (0.74) | GCKLMNAMEN1NPC1KMT2A | |
| SCHEMBL2642521 | 0.79 | GCK (0.73) | GCKLMNAMEN1NPC1KMT2A | |
| SCHEMBL2643351 | 0.79 | GCK (0.63) | GCK | |
| SCHEMBL2642304 | 0.78 | GCK (0.59) | GCKLMNANPC1HDAC1KDM4E | |
| SCHEMBL2642482 | 0.77 | GCK (0.67) | GCKLMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2643431 | 0.76 | GCK (0.78) | GCK | |
| SCHEMBL14430958 | 0.76 | GCK (0.74) | GCK | |
| SCHEMBL2642588 | 0.72 | GCK (0.66) | GCKNPC1HPGDHDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |