Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430973 | 0.87 | GCK (0.60) | GCKLMNA | |
| SCHEMBL2642304 | 0.82 | GCK (0.59) | GCKLMNARAB9A | |
| SCHEMBL2643624 | 0.80 | GCK (0.74) | GCKLMNARAB9A | |
| SCHEMBL2642521 | 0.79 | GCK (0.73) | GCKLMNARAB9A | |
| SCHEMBL2642482 | 0.77 | GCK (0.67) | GCKLMNA | |
| SCHEMBL2642624 | 0.76 | GCK (0.82) | GCK | |
| SCHEMBL2643506 | 0.71 | GCK (1.00) | GCK | |
| SCHEMBL2642744 | 0.70 | GCK (0.72) | GCK | |
| SCHEMBL14430959 | 0.69 | GCK (0.59) | GCK | |
| SCHEMBL2643522 | 0.69 | GCK (0.84) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |