Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447959 | 0.86 | KDM4E (0.43) | KDM4ETDP1ENPP2MMP3 | |
| SCHEMBL8657492 | 0.86 | KDM4E (0.43) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL1019992 | 0.86 | KDM4E (0.43) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL25170271 | 0.77 | CA12 (0.48) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL1072135 | 0.77 | KDM4E (0.41) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL25808872 | 0.77 | KDM4E (0.37) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL1401399 | 0.77 | CYP4F2 (0.41) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL332715 | 0.77 | KDM4E (0.37) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL20576683 | 0.77 | KDM4E (0.37) | KDM4ETDP1ENPP2CYP11B1CYP11B2 | |
| SCHEMBL25990556 | 0.77 | KDM4E (0.37) | KDM4ETDP1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490371-B1 | THIOPHENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL MYERS SQUIBB CO (US) | 2007-08-15 | — | — | EP | disclosed |