Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27347770 | 0.86 | KMT2A (0.55) | PARP1L3MBTL1ANPEPENPEPACP3 | |
| SCHEMBL2858374 | 0.86 | KMT2A (0.55) | PARP1L3MBTL1ANPEPENPEPACP3 | |
| SCHEMBL3510648 | 0.86 | KMT2A (0.55) | PARP1L3MBTL1ANPEPENPEPACP3 | |
| SCHEMBL11075538 | 0.84 | PARP1 (0.47) | PARP1L3MBTL1ACP3SMN1; SMN2CYP2C19 | |
| SCHEMBL7562318 | 0.83 | PARP1 (0.46) | PARP1L3MBTL1ACP3CYP2C19TDP1 | |
| SCHEMBL12883182 | 0.83 | PARP1 (0.46) | PARP1L3MBTL1ACP3CYP2C19TDP1 | |
| SCHEMBL18516122 | 0.82 | AOC3 (0.43) | L3MBTL1ANPEPENPEPACP3KMT2A | |
| SCHEMBL15471647 | 0.81 | TDP1 (0.45) | PARP1L3MBTL1ACP3CYP2C19TDP1 | |
| SCHEMBL7107654 | 0.81 | KYNU (0.51) | PARP1L3MBTL1ANPEPENPEPKMT2A | |
| SCHEMBL17210729 | 0.79 | KMT2A (0.48) | PARP1L3MBTL1ANPEPENPEPACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490371-B1 | THIOPHENE-BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | BRISTOL MYERS SQUIBB CO (US) | 2007-08-15 | — | — | EP | disclosed |