SCHEMBL14432305

SCHEMBL14432305

COCCCN1CCOc2ccc(CO[C@H]3CNC[C@@H](OCC(C)O)[C@@H]3c3ccc(COC[C@@H](C)COC)cc3)cc21

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 14/20 0.39
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2690670 1.00 REN (0.39) RENRORC
SCHEMBL2684624 1.00 REN (0.39) RENRORC
SCHEMBL2684621 1.00 REN (0.39) RENRORC
SCHEMBL2690222 0.95 REN (0.40) REN
SCHEMBL2690221 0.95 REN (0.40) REN
SCHEMBL3943127 0.95 REN (0.40) REN
SCHEMBL2683885 0.95 REN (0.39) RENRORC
SCHEMBL2683887 0.95 REN (0.39) RENRORC
SCHEMBL2692846 0.95 REN (0.39) RENRORC
SCHEMBL2683908 0.94 REN (0.37) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1816122-A2 3,4,5-substituted piperidines as therapeutic compounds Speedel Experimenta AG (CH) 2007-08-08 EP disclosed