SCHEMBL1443301

SCHEMBL1443301

O=c1[nH]c(NCc2ccc(Cl)c(Cl)c2)nc2ncn(CCCCCN3CCOCC3)c12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1443761 0.99
SCHEMBL1443265 0.99
Hydrochloric Acid SCHEMBL1443775 0.98
SCHEMBL12173570 0.97
Hydrochloric Acid SCHEMBL15909144 0.97
Ibezapolstat SCHEMBL15908884 0.95
Ibezapolstat SCHEMBL29357391 0.95
Ibezapolstat SCHEMBL15908913 0.94
SCHEMBL1443985 0.94
SCHEMBL1443302 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120232077-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS ACURX PHARMACEUTICALS, LLC 2012-09-13 US claimed
EP-2475252-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS Glsynthesis Inc. (US) 2012-07-18 EP claimed
WO-2011031935-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS GLSYNTHESIS INC. (US) 2011-03-17 WO claimed
EP-2475252-B1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS GLSYNTHESIS INC (US) 2016-11-16 EP disclosed
US-8796292-B2 Selective antibacterials for clostridium difficile infections GLSYNTHESIS INC. (US) 2014-08-05 US disclosed
US-8796292-B2 Selective antibacterials for clostridium difficile infections GLSYNTHESIS INC. (US) 2014-08-05 US disclosed
US-8796292-B2 Selective antibacterials for clostridium difficile infections GLSYNTHESIS INC. (US) 2014-08-05 US disclosed
US-20120232077-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS ACURX PHARMACEUTICALS, LLC 2012-09-13 US disclosed
US-20120232077-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS ACURX PHARMACEUTICALS, LLC 2012-09-13 US disclosed
US-20120232077-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS ACURX PHARMACEUTICALS, LLC 2012-09-13 US disclosed
EP-2475252-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS Glsynthesis Inc. (US) 2012-07-18 EP disclosed
WO-2011031935-A1 SELECTIVE ANTIBACTERIALS FOR CLOSTRIDIUM DIFFICILE INFECTIONS GLSYNTHESIS INC. (US) 2011-03-17 WO disclosed