Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TST | Q16762 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244667 | 0.84 | KMT2A (0.70) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL5243266 | 0.83 | KMT2A (0.69) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL5281337 | 0.81 | KMT2A (0.66) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL5284552 | 0.80 | POLB (0.63) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL14433266 | 0.80 | KMT2A (0.76) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL8160125 | 0.79 | ALDH1A1 (0.69) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL5290647 | 0.78 | KMT2A (0.53) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL5247001 | 0.78 | KMT2A (0.73) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL5284612 | 0.77 | KMT2A (0.61) | KMT2APTPN2PTPN1PTPN5HSPD1 | |
| SCHEMBL6390668 | 0.77 | KMT2A (0.68) | KMT2APTPN2PTPN1PTPN5HSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262204-B2 | Modulation of CCR4 function | AMGEN INC. (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262204-B2 | Modulation of CCR4 function | AMGEN INC. (US) | 2007-08-28 | — | — | US | disclosed |