SCHEMBL1443386

SCHEMBL1443386

CC1(C)CC=CCC1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
APLNR P35414 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1989180 0.79 MEN1 (0.36) SLC1A2SLC1A1APLNR
SCHEMBL1285662 0.79 MEN1 (0.36) SLC1A2SLC1A1APLNR
SCHEMBL1926380 0.79 MEN1 (0.36) SLC1A2SLC1A1APLNR
SCHEMBL10740811 0.79 MEN1 (0.36) SLC1A2SLC1A1APLNR
SCHEMBL7025871 0.75
SCHEMBL10476965 0.74 MEN1 (0.33)
SCHEMBL5868459 0.71
SCHEMBL28747389 0.71
SCHEMBL28405609 0.70 MEN1 (0.33)
SCHEMBL5649474 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109265400-B Arginine methyltransferase inhibitors and uses thereof EPIZYME股份有限公司 2022-10-04 CN disclosed
WO-2016106623-A1 BENZAMIDE IMIDAZOPYRAZINE BTK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2016-07-07 WO disclosed
EP-2507249-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES Gilead Sciences, Inc. (US) 2012-10-10 EP disclosed
WO-2011031669-A1 INHIBITORS OF FLAVIVIRIDAE VIRUSES GILEAD SCIENCES, INC. (US) 2011-03-17 WO disclosed