Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.85 |
| ▸ | DRD1 | P21728 | 1/20 | 0.85 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.85 |
| ▸ | PDE4A | P27815 | 1/20 | 0.85 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGAV | P06756 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.37 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.37 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.37 |
| ▸ | NECTIN4 | Q96NY8 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 7/20 | 0.36 |
| ▸ | MC5R | P33032 | 7/20 | 0.36 |
| ▸ | MC3R | P41968 | 7/20 | 0.36 |
| ▸ | MC1R | Q01726 | 7/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | SHH | Q15465 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13246717 | 0.96 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8226898 | 0.96 | CTSL (0.84) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8230275 | 0.96 | CTSL (0.84) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8230288 | 0.96 | CTSL (0.84) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8226972 | 0.96 | CTSL (0.84) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8227054 | 0.95 | CTSL (0.85) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8230311 | 0.94 | CTSL (0.96) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8358323 | 0.94 | CTSL (0.91) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8422141 | 0.93 | CTSL (0.92) | CTSLDRD1PTGS1PDE4AEPHA2 | |
| SCHEMBL8354268 | 0.92 | CTSL (0.86) | CTSLDRD1PTGS1PDE4AEPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262268-B2 | Lipopeptide stereoisomers, methods for preparing same, and useful intermediates | CUBIST PHARMACEUTICALS, INC. (US) | 2007-08-28 | — | — | US | disclosed |