Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | CFD | P00746 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434667 | 0.94 | F10 (0.40) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL14434666 | 0.92 | F10 (0.41) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL12371495 | 0.92 | F10 (0.41) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL12101413 | 0.87 | F10 (0.43) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL12371497 | 0.86 | F10 (0.40) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL12101298 | 0.85 | F10 (0.42) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL14434665 | 0.84 | F10 (0.41) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL12101302 | 0.84 | F10 (0.41) | F10CFDTSHRKLKB1KMT2A | |
| SCHEMBL12371498 | 0.83 | F10 (0.41) | F10CFDTSHRKLKB1CYP2C9 | |
| SCHEMBL14434256 | 0.83 | F10 (0.41) | F10CFDTSHRKLKB1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093595-A1 | SUBSTITUTED PROLINAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |