Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.70 |
| ▸ | DRD1 | P21728 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.34 |
| ▸ | ITGAV | P06756 | 9/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.34 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.34 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | NPR1 | P16066 | 1/20 | 0.33 |
| ▸ | NPR3 | P17342 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434171 | 1.00 | CTSL (0.70) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL14434101 | 0.96 | CTSL (0.74) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8227164 | 0.95 | CTSL (0.69) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8221738 | 0.95 | CTSL (0.69) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8226890 | 0.92 | CTSL (0.73) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8227065 | 0.92 | CTSL (0.74) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8221749 | 0.91 | CTSL (0.66) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8230343 | 0.90 | CTSL (0.67) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8354165 | 0.90 | CTSL (0.73) | CTSLDRD1PTGS1PDE4AKEAP1 | |
| SCHEMBL8227051 | 0.89 | CTSL (0.79) | CTSLDRD1PTGS1PDE4AALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262268-B2 | Lipopeptide stereoisomers, methods for preparing same, and useful intermediates | CUBIST PHARMACEUTICALS, INC. (US) | 2007-08-28 | — | — | US | disclosed |