Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.58 |
| ▸ | PPARA | Q07869 | 9/20 | 0.58 |
| ▸ | PPARG | P37231 | 8/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515765 | 1.00 | PPARD (0.58) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL5517534 | 0.85 | PPARD (0.79) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL5516731 | 0.84 | PPARD (0.64) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL3917956 | 0.80 | PPARA (0.52) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3917946 | 0.80 | PPARA (0.52) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6243594 | 0.77 | PPARD (0.75) | PPARDPPARAPPARGFFAR1CHRM5 | |
| SCHEMBL5526130 | 0.77 | PPARD (0.66) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL14571496 | 0.77 | PPARA (0.61) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5508404 | 0.77 | PPARD (0.82) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5850587 | 0.77 | PPARA (0.49) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259175-B2 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-08-21 | — | — | US | disclosed |
| US-7259175-B2 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-08-21 | — | — | US | disclosed |