Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13993791 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHRH2HRH1 | |
| SCHEMBL14260140 | 0.83 | CYP2D6 (0.38) | ALDH1A1KDM4EPOLBHRH2HRH1 | |
| SCHEMBL13944149 | 0.79 | USP2 (0.44) | ALDH1A1HTTSMN1; SMN2RECQL | |
| SCHEMBL22014309 | 0.79 | TSHR (0.50) | ALDH1A1KDM4EPOLBGAAPPARD | |
| SCHEMBL15599233 | 0.77 | HRH2 (0.45) | KDM4EHRH2HRH1PIK3CD | |
| SCHEMBL12283671 | 0.76 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBHTTSMN1; SMN2 | |
| SCHEMBL27979621 | 0.75 | — | — | |
| SCHEMBL26317513 | 0.75 | TSHR (0.43) | ALDH1A1POLBHRH2HRH1HTT | |
| SCHEMBL15832599 | 0.74 | HRH2 (0.52) | ALDH1A1KDM4EHRH2HRH1HTT | |
| SCHEMBL19400534 | 0.74 | HRH2 (0.42) | ALDH1A1POLBHRH2HRH1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185007-A1 | Aza-quinolinol phosphonate integrase inhibitor compounds | JIN HAOLUN | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185007-A1 | Aza-quinolinol phosphonate integrase inhibitor compounds | CDKL5, CDKL1, CDKL3 | ALDH1A1 2811/4885KDM4E 303/4885POLB 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.