Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127393 | 0.81 | AKR1C2 (0.45) | CA5ACYP3A4HPGDHSD17B10CRHBP | |
| SCHEMBL23087599 | 0.79 | ALDH1A1 (0.42) | HPGDHSD17B10MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL83132 | 0.77 | CYP3A4 (0.58) | CYP3A4HPGDHSD17B10CRHBPCRHR2 | |
| SCHEMBL14753933 | 0.75 | MEN1 (0.40) | CYP3A4HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL22102214 | 0.75 | CYP4F2 (0.41) | CYP3A4HPGDHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL4119971 | 0.75 | ALDH1A1 (0.49) | CA5ACYP3A4HPGDHSD17B10CRHBP | |
| Ammonia Solution, Strong SCHEMBL10706299 | 0.74 | CYP3A4 (0.55) | CYP3A4HPGDHSD17B10CRHBPCRHR2 | |
| SCHEMBL5460462 | 0.72 | HSD17B10 (0.50) | CYP3A4HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL29507215 | 0.72 | HSD17B10 (0.50) | CYP3A4HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL7306944 | 0.72 | HSD17B10 (0.50) | CYP3A4HPGDHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007090434-A1 | SUBSTITUTED ARYL OXIMES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | WO | disclosed |