Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511981 | 1.00 | MEN1 (0.42) | MEN1KMT2ALTA4HSMN1; SMN2POLB | |
| SCHEMBL13132269 | 1.00 | MEN1 (0.42) | MEN1KMT2ALTA4HSMN1; SMN2POLB | |
| SCHEMBL13547722 | 0.98 | MEN1 (0.46) | MEN1KMT2ALTA4HSMN1; SMN2POLB | |
| SCHEMBL23205839 | 0.98 | MEN1 (0.46) | MEN1KMT2ALTA4HSMN1; SMN2POLB | |
| SCHEMBL13547720 | 0.81 | POLB (0.45) | MEN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL9432545 | 0.79 | TLR9 (0.30) | — | |
| SCHEMBL12125079 | 0.79 | USP2 (0.50) | MEN1KMT2ASMN1; SMN2USP2TSHR | |
| SCHEMBL20349515 | 0.79 | DRD2 (0.33) | SMN1; SMN2POLB | |
| SCHEMBL23205826 | 0.79 | USP2 (0.50) | MEN1KMT2ASMN1; SMN2USP2TSHR | |
| SCHEMBL18390141 | 0.79 | DRD2 (0.33) | SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021063346-A1 | KRAS G12C INHIBITOR AND APPLICATION THEREOF | 上海迪诺医药科技有限公司 | 2021-04-08 | — | — | WO | disclosed |
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |